Recombinant Rabbit Monoclonal Antibody to Desmin (DESM) (Clone: RM234)(Discontinued)
Figure 1: Western Blot of mouse heart tissue lysates using Anti-Desmin Clone: RM234 at a 1:1000 dilution, showed a band of Desmin (~54 kDa) expressed in mouse heart.
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Purification : | Protein A affinity purified from an animal origin-free culture supernatant |
| Content : | Antibody in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Storage condition : | Store at -20°C. Avoid repeated freeze and thaw cycles. |
Clone RM234 reacts to human and mouse Desmin. This antibody may also react to rat and Bovine Desmin, as predicted by immunogen homology. Immunohistochemistry (IHC): 1:1000-1:4000 dilution; Western Blot (WB): 1:1000-1:2000 dilution.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Cytoplasm, Cell membrane, Nucleus |
| Post transnational modification: | Phosphorylation at Ser-7, Ser-28 and Ser-32 by CDK1, phosphorylation at Ser-60 by AURKB and phosphorylation at Thr-76 by ROCK1 contribute to efficient separation of desmin intermediate filaments during mitosis. |
| BioGrid: | 108038. 47 interactions. |
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