Recombinant Rabbit Monoclonal Antibody to Cyclin D1 (CCND1)(Clone: RM241)(Discontinued)
Figure 1: Western Blot of HeLa cell lysates using Anti-Cyclin D1 Clone: RM241 at a 1:1000 dilution, showed a band of Cyclin D1 (~34 kDa) expressed in HeLa cells.
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Purification : | Protein A affinity purified from an animal origin-free culture supernatant |
| Content : | Antibody in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
| Storage condition : | Store at -20°C. Avoid repeated freeze and thaw cycles. |
Clone RM241 reacts to human Cyclin D1. This antibody may also react to bovine, mouse or rat Cyclin D1, as predicted by immunogen homology. Immunohistochemistry (IHC): 1:500-1:1000 dilution; Western Blot (WB): 1:1000-1:2000 dilution.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Cytoplasm, Membrane |
| Post transnational modification: | Phosphorylation at Thr-286 by MAP kinases is required for ubiquitination and degradation following DNA damage. It probably plays an essential role for recognition by the FBXO31 component of SCF (SKP1-cullin-F-box) protein ligase complex. |
| BioGrid: | 107067. 101 interactions. |
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