Recombinant Rabbit Monoclonal Antibody to Cyclin D1 (CCND1)(Clone: RM241)(Discontinued)

Product code: 10-9603

Clone name : RM241
Clonality : Monoclonal
Application : WB, IHC
Reactivity : Human, Bovine, Mouse , Rat

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Purification : Protein A affinity purified from an animal origin-free culture supernatant
Content : Antibody in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Storage condition : Store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : CCND1
Gene ID :  595
Uniprot ID : P24385
Alternative Name : CCND1, BCL1, PRAD1
Immunogen Information : A peptide corresponding to Cyclin D1

Clone RM241 reacts to human Cyclin D1. This antibody may also react to bovine, mouse or rat Cyclin D1, as predicted by immunogen homology. Immunohistochemistry (IHC): 1:500-1:1000 dilution; Western Blot (WB): 1:1000-1:2000 dilution.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus, Cytoplasm, Membrane
Post transnational modification: Phosphorylation at Thr-286 by MAP kinases is required for ubiquitination and degradation following DNA damage. It probably plays an essential role for recognition by the FBXO31 component of SCF (SKP1-cullin-F-box) protein ligase complex.
BioGrid: 107067. 101 interactions.
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