Polyclonal antibody to Mouse TRAF-1

Product code: 20-1094

Clonality : Polyclonal
Application : IP, IHC, WB
Reactivity : Mouse

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Size
Price
50 µl
$260.00 

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Shipping Info:

Order now and get it on Wednesday November 06, 2024

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Format : Sera
Amount : 50 µl
Isotype : Rabbit IgG
Content : 50 µl sera
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : Traf1
Gene ID : 22029
Uniprot ID : P39428
Alternative Name : TNF receptor-associated factor 1
Immunogen Information : A synthetic peptide of mouse TRAF-1 ( amino acids 51-69 CRADNLHPVSPGSPLTQEK) was used as immunogen for this antibody

This antibody recognizes TRAF1. Mouse TRAF1 is a 409 amino acid protein.TRAF1 is a member of TRAF (TNF receptor-associated factor) adapter proteins composed 416 amino acids. The members of this family link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases. TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. TRAFs also interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.

WB: 1:1000-1:2000, IHC (paraffin): 1:1000-1:5000, IHC (frozen): Users should optimize, IP: 1:50-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: Polyubiquitinated by BIRC2 and/or BIRC3, leading to its subsequent proteasomal degradation.
BioGrid: 204302. 6 interactions.
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