Polyclonal Antibody to Synaptotagmin 1 (Ab-309)

Product code: 35-1621

Clonality : Polyclonal
Application : WB, IF
Reactivity : Rat, Mouse, Human

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : SYT1
Gene ID : 6857
Uniprot ID : P21579
Alternative Name : SYT1, SytI, Synaptotagmin I, P65, SYT
Immunogen Information : Peptide sequence around aa.307~311 (G-L-S-D-P) derived from Human Synaptotagmin 1.

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18(5):1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18(12):4957-68.

Predicted MW: 60-65kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasmic vesicle, Cytoplasmic vesicle, Cytoplasmic vesicle, Cytoplasm
Tissue Specificity: Expressed in melanocytes (PubMed:23999003).
BioGrid: 112723. 41 interactions.
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