Polyclonal Antibody to Synaptophysin

Product code: 35-1819

Clonality : Polyclonal
Application : WB
Reactivity : Rat, Mouse, Human

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : SYP
Gene ID : 6855
Uniprot ID : P08247
Alternative Name : MRXSYP
Immunogen Information : Peptide sequence around aa.305~309(A-P-T-S-F) derived from Human Synaptophysin

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity "Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex."

Predicted MW: 38kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasmic vesicle, Cell junction
Post transnational modification: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
Tissue Specificity: Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3.
BioGrid: 112721. 39 interactions.
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