Polyclonal Antibody to Raf1 (Phospho-Ser338)

Product code: 35-1191

Clonality : Polyclonal
Application : WB
Reactivity : Human, Mouse, Rat

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : RAF1
Gene ID : 5894
Uniprot ID : P04049
Alternative Name : C-RAF, C-Raf, CRAF
Immunogen Information : Peptide sequence around phosphorylation site of serine 338 (R-D-S(p)-S-Y) derived from Human RAF.
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.

Predicted MW: 73kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Cell membrane, Mitochondrion, Nucleus
Post transnational modification: Methylated at Arg-563 in response to EGF treatment. This modification leads to destabilization of the protein, possibly through proteasomal degradation.
Tissue Specificity: In skeletal muscle, isoform 1 is more abundant than isoform 2.
BioGrid: 111831. 174 interactions.
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