Polyclonal Antibody to PER2

Product code: 11-8072

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $100.00 

  • $270.00 

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Shipping Info:

Order now and get it on Tuesday November 26, 2024

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Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : PER2
Gene ID : 8864
Uniprot ID : O15055
Alternative Name : PER2, KIAA0347
Immunogen Information : A partial length recombinant PER2 protein (amino acids 700-900) was used as the immunogen for this antibody.
PER2 gene encodes the period circadian protein homolog 2 protein in humans. PER2 is a component of the circadian clock mechanism which is essential for generating circadian rhythms. Diseases associated with PER2 include advanced sleep phase syndrome and familial advanced sleep phase syndrome 1. PER2 is widely expressed in heart, brain, placenta, skeletal muscle, kidney and pancreas. It has two Isoform of 136 and 45 kDa.

Western blot analysis: 2-4 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
Post transnational modification: Ubiquitinated, leading to its proteasomal degradation. Ubiquitination may be inhibited by CRY1.
Tissue Specificity: Widely expressed. Found in heart, brain, placenta, lung, liver, skeleatal muscle, kidney and pancreas. High levels in skeletal muscle and pancreas. Low levels in lung. Isoform 2 is expressed in keratinocytes (at protein level).
BioGrid: 114387. 18 interactions.
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