Polyclonal Antibody to PER2
Fig-1: Western blot analysis of PER2. Anti-PER2 antibody (11-8072) was used at 2 µg/ml on Testis lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
PER2 gene encodes the period circadian protein homolog 2 protein in humans. PER2 is a component of the circadian clock mechanism which is essential for generating circadian rhythms. Diseases associated with PER2 include advanced sleep phase syndrome and familial advanced sleep phase syndrome 1. PER2 is widely expressed in heart, brain, placenta, skeletal muscle, kidney and pancreas. It has two Isoform of 136 and 45 kDa.
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Post transnational modification: | Ubiquitinated, leading to its proteasomal degradation. Ubiquitination may be inhibited by CRY1. |
| Tissue Specificity: | Widely expressed. Found in heart, brain, placenta, lung, liver, skeleatal muscle, kidney and pancreas. High levels in skeletal muscle and pancreas. Low levels in lung. Isoform 2 is expressed in keratinocytes (at protein level). |
| BioGrid: | 114387. 18 interactions. |
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