Polyclonal Antibody to LIMK2 (Phospho-Thr505)

Product code: 35-1123

Clonality : Polyclonal
Application : WB, IHC, IF
Reactivity : Human, Mouse, Rat

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : LIMK2
Gene ID : 3985
Uniprot ID : P53671
Alternative Name : LIMK-2, kinase LIMK2
Immunogen Information : Peptide sequence around phosphorylation site of threonine 505 (R-Y-T(p)-V-V) derived from Human LIMK2.
Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.

Predicted MW: 70kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Nucleus
Post transnational modification: Phosphorylated on serine and/or threonine residues by ROCK1.
Tissue Specificity: Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.
BioGrid: 110173. 37 interactions.
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