Polyclonal Antibody to LC3A

Product code: 35-1658

Clonality : Polyclonal
Application : WB, IF
Reactivity : Human, Mouse, Rat

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : MAP1LC3A
Gene ID : 84557
Uniprot ID : Q9H492
Alternative Name : Microtubule-associated protein 1 light chain 3 alpha, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1 light chain 3-like protein 1, Autophagy-related protein LC3 A
Immunogen Information : Peptide sequence around aa.5~10 (R-P-F-K-Q) derived from Human LC3A.
Probably involved in formation of autophagosomal vacuoles (autophagosomes).

Predicted MW: 18 16 kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Endomembrane system, Cytoplasmic vesicle, Cytoplasmic vesicle
Post transnational modification: Phosphorylation at Ser-12 by PKA inhibits conjugation to phosphatidylethanolamine (PE). Interaction with MAPK15 reduces the inhibitory phosphorylation and increases autophagy activity.
Tissue Specificity: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
BioGrid: 124137. 121 interactions.
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