Polyclonal Antibody to JAK1 (Ab-1022)

Figure 1: Western blot analysis of extracts from 3T3, HepG2, HT29 and MDA cells using JAK1 (Ab-1022) Antibody 35-1469 .

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For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	100 µl
Isotype :	Rabbit IgG
Content :	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	JAK1
Gene ID :	3716
Uniprot ID :	P23458
Alternative Name :	Janus kinase 1
Immunogen Information :	Peptide sequence around aa. 1020~1024 (K-E-Y-Y-T) derived from Human JAK1.

Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

Predicted MW: 130kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Endomembrane system
Post transnational modification:	Ubiquitinated by RNF125; leading to its degradation by the proteasome.
Tissue Specificity:	Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.
BioGrid:	109919. 107 interactions.