Polyclonal Antibody to HSP90B (Phospho-Ser254)

Product code: 35-1185

Clonality : Polyclonal
Application : WB
Reactivity : Human, Mouse

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : HSP90AB1
Gene ID : 3326
Uniprot ID : P08238
Alternative Name : HS90B, HSP 84, HSP90-beta, HSP90AB1, HSPC2
Immunogen Information : Peptide sequence around phosphorylation site of serine 254 (V-G-S(p)-D-E) derived from Human HSP90B.
Molecular chaperone. Has ATPase activity. Zhao R, Houry WA.(2007) Adv Exp Med Biol; 594: 27-36. Olsen JV, et al. (2006) Cell; 127(3): 635-648 Ogiso H, et al. (2004) Biochemistry; 43(49): 15510-15519

Predicted MW: 92kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Melanosome, Nucleus, Secreted, Cell membrane
Post transnational modification: Cleaved following oxidative stress resulting in HSP90AB1 protein radicals formation; disrupts the chaperoning function and the degradation of its client proteins.
BioGrid: 109558. 383 interactions.
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