Polyclonal Antibody to HSP90B (Phospho-Ser254)
Figure 1: Western blot analysis of extracts from Hela cells untreated(lane 1) or treated with hot shock(lane 2) using HSP90B(Phospho-Ser254) Antibody 35-1185 .
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Shipping Info:
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Molecular chaperone. Has ATPase activity.
Zhao R, Houry WA.(2007) Adv Exp Med Biol; 594: 27-36.
Olsen JV, et al. (2006) Cell; 127(3): 635-648
Ogiso H, et al. (2004) Biochemistry; 43(49): 15510-15519
Predicted MW: 92kd, Western blotting: 1:500~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Melanosome, Nucleus, Secreted, Cell membrane |
| Post transnational modification: | Cleaved following oxidative stress resulting in HSP90AB1 protein radicals formation; disrupts the chaperoning function and the degradation of its client proteins. |
| BioGrid: | 109558. 383 interactions. |
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