Polyclonal Antibody to Her3/ErbB3 (phospho-Tyr1328)

Figure 1: Western blot analysis of extracts from A431 cells untreated or treated with EGF using Her3/ErbB3(phospho-Tyr1328) Antibody 35-1307 .

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For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	100 µl
Isotype :	Rabbit IgG
Content :	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	ERBB3
Gene ID :	2065
Uniprot ID :	P21860
Alternative Name :	Tyrosine kinase-type cell surface receptor HER3
Immunogen Information :	Peptide sequence around phosphorylation site of tyrosine 1328 (P-D-Y(p)-W-H) derived from Human Her3/ErbB3.

Binds and is activated by neuregulins and NTAK.

Predicted MW: 185kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Secreted
Post transnational modification:	Autophosphorylated (PubMed:20351256). Ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778).
Tissue Specificity:	Epithelial tissues and brain.
BioGrid:	108377. 187 interactions.