Polyclonal Antibody to Exportin-4
Fig-1: Western blot analysis of Exportin-4. Anti- Exportin-4 antibody (11-8014) was used at 1 µg/ml on Heart lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Exportin-4 or XPO4 belongs to a large family of nucleoproteins that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments. Exportin-4 is a RanGTP-binding protein and functions as a receptor for nuclear export of EIF-5A and also may have a role as an adapter in RNA export. Exportin-4 has been reported to be involved in nuclear export of Smad3 and thereby regulation of Smad signaling. Diseases associated with XPO4 include pinguecula. This protein has ubiquitously expressed.
Western blot analysis: 1-3 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus |
| BioGrid: | 122138. 56 interactions. |
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