Polyclonal Antibody to coflin1/cofilin2 (Ab-88)
Figure 1: Western blot analysis of extracts from MDA cells using cofilin1/cofilin2(Ab-88) Antibody 35-1724 .
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | CFL1 |
| Gene ID : | 1072 |
| Uniprot ID : | P23528/ Q9Y281 |
| Alternative Name : | Cofilin, non-muscle isoform 18 kDa phosphoprotein |
| Immunogen Information : | Peptide sequence around aa. 86~90 (A-T-Y-E-T) derived from Human cofilin1/cofilin2. |
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830.
Arber, S. et al. (1998) Nature 393, 805-809.
Yang, N. et al. (1998) Nature 393, 809-812.
Predicted MW: 19kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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