Polyclonal Antibody to CDC2 (Phospho-Tyr15)
Figure 1: Western blot analysis of extracts from Hela cells untreated(lane 1) or treated with UV(lane 2) using CDC2(Phospho-Tyr15) Antibody 35-1226 .
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
Y Gu, et al. (1992) EMBO J. 11(11): 3995
Predicted MW: 34kd, Western blotting: 1:500~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Cytoplasm, Mitochondrion, Cytoplasm, Cytoplasm |
| Post transnational modification: | Polyubiquitinated upon genotoxic stress. |
| Tissue Specificity: | Isoform 2 is found in breast cancer tissues. |
| BioGrid: | 107420. 287 interactions. |
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