Polyclonal Antibody to CD34
Figure 1: Western blot analysis of extract from HUVEC cells and Hematopoietic Stem Cells from Umbilical Cord Blood using CD34 Antibody 35-1700
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Predicted MW: 110kd, Western blotting: 1:500~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane |
| Post transnational modification: | Phosphorylated on serine residues by PKC. |
| Tissue Specificity: | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
| BioGrid: | 107385. 1 interactions. |
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