Polyclonal Antibody to beta-Catenin (Phospho-Thr41/Ser45)
Figure 1: Western blot analysis of extracts from SW626 cells using b-Catenin(Phospho-Thr41/Ser45) Antibody 35-1113 (Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Rabbit IgG |
| Content : | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.
Provost E, et al. (2003)J Biol Chem 22; 278(34): 31781-9.
Sakanaka C , et al. (2003)J Biochem (Tokyo); 132(5): 697-703.
Amit S, et al. (2002) Genes Dev; 16(9): 1066-76.
Liu C, et al. (2002) Cell; 108(6): 837-47.
Provost E, et al. (2005) Oncogene; 24(16): 2667-76.
Predicted MW: 92kd, Western blotting: 1:500~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus, Cytoplasm, Cell junction, Cell junction, Cell membrane, Cytoplasm, Cytoplasm, Cell junction, Cytoplasm |
| Post transnational modification: | Deacetylated at Lys-49 by SIRT1. |
| Tissue Specificity: | Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level). Expressed in breast cancer tissues (at protein level) (PubMed:29367600). |
| BioGrid: | 107880. 630 interactions. |
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