Polyclonal Antibody to ASPSCR1

Product code: 35-1682

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Available Pack Size(s)

  •   50 µl

  •  100 µl

  • $374.00 

  • $437.00 

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Format : Purified
Amount : 100 µl
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : ASPSCR1
Gene ID : 79058
Uniprot ID : Q9BZE9
Alternative Name : ASPL, RCC17, TUG, UBXD9, UBXN9
Immunogen Information : Peptide sequence around aa.303 ~307(P-Q-Q-E-Q) derived from Human ASPSCR1.
Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.

Predicted MW: 70-75kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Endomembrane system, Endoplasmic reticulum-Golgi intermediate compartment membrane, Cytoplasm, Nucleus
Tissue Specificity: Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas.
BioGrid: 122516. 53 interactions.
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