Mouse Monoclonal Antibody to SUMO1 (Clone: 66AT1320)(Discontinued)
Figure 1: The anti-SUMO1 monoclonal antibody(10-6520 ) is used in Western blot to detect SUMO1 in HL60 cell lysate.
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| Format : | Purified |
| Amount : | 400 µl |
| Isotype : | Mouse IgG1 |
| Purification : | Protein G Chromatography |
| Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
WB~1:100~500
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus membrane, Nucleus speckle, Cytoplasm, Nucleus, Cell membrane, Nucleus |
| Post transnational modification: | Polymeric SUMO1 chains undergo polyubiquitination by RNF4. |
| BioGrid: | 113188. 169 interactions. |
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