Mouse Monoclonal Antibody to LOX (Center)(Clone: 624CT23.7.3)(Discontinued)
Figure 1: Western blot analysis of LOX Antibody (10-6588) in MDA-MB231 cell line lysates (35μg/lane). This demonstrates the LOX antibody detected the LOX protein.
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| Format : | Purified |
| Amount : | 400 µl |
| Isotype : | Mouse IgG2b |
| Purification : | Protein G Chromatography |
| Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and
elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
WB~1:100~500
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted, Secreted |
| Post transnational modification: | Proteolytically activated by BMP1. |
| Tissue Specificity: | Heart, placenta, skeletal muscle, kidney, lung and pancreas. |
| BioGrid: | 110199. 20 interactions. |
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