Mouse Monoclonal Antibody to LAMP2 (Clone: 157CT16.6.6)(Discontinued)
Figure 1: Western blot analysis of LAMP2 Antibody (10-6540) in mouse NIH-3T3 cell line lysates (35μg/lane). This demonstrates the LAMP2 antibody detected the LAMP2 protein.
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| Format : | Purified |
| Amount : | 400 µl |
| Isotype : | Mouse IgG1,Kappa |
| Purification : | Protein G Chromatography |
| Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter-and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
WB~1:100~1000|| IF~1:10~50
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane, Endosome membrane, Lysosome membrane, Cytoplasmic vesicle |
| Post transnational modification: | O- and N-glycosylated; some of the 16 N-linked glycans are polylactosaminoglycans. |
| Tissue Specificity: | Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle (PubMed:7488019, PubMed:26856698). Isoform LAMP-2B is detected in spleen, thymus, prostate, testis, small intestine, colon, skeletal muscle, brain, placenta, lung, kidney, ovary and pancreas and liver (PubMed:7488019, PubMed:26856698). Isoform LAMP-2C is detected in small intestine, colon, heart, brain, skeletal muscle, and at lower levels in kidney and placenta (PubMed:26856698). |
| BioGrid: | 110114. 96 interactions. |
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