Mouse Monoclonal Antibody to Human PD-1 (Clone : PD1.D3)

Product code: 45-1074

Clone name : PD1.D3
Clonality : Monoclonal
Application : ELISA

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Size
Price
40 µg
$351.00 

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Format : Purified
Amount : 40 µg
Isotype : Mouse IgG1,Kappa
Purification : Protein A chromatography
Content : 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Storage condition : The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Gene : PDCD1
Gene ID : 5133
Uniprot ID : Q15116
Alternative Name : Programmed cell death protein 1, Protein PD-1, hPD-1, CD279
Immunogen Information : Recombinant human PD-1-Fc

Programmed cell death protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. Binding of its two ligands PD-L1 and PD-L2 could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and popular target for therapeutic antibodies against many cancers. Anti-Human PD-1 Antibody (PD1.D3), mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from mouse immunized with recombinant human PD-1-Fc .

ELISA detection: 0.01-0.1 µg/ml
ELISA blocking: 10-15 µg/ml
Flow cytometry: 5-10 µg/ml
Blockade of Receptor-ligand Interaction in Flow cytometry: 5 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Membrane
BioGrid: 111160. 61 interactions.
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