Mouse Monoclonal Antibody to Cytokeratin AE1/AE3(Clone: AE1+AE3)(Discontinued)

Product code: 10-11514

Clone name : AE1+AE3
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG1, Kappa
Content : This antibody is supplied as purified IgG and contains sodium azide as preservative.
Storage condition : Store at 2-8°C.
Gene : KRT1
Gene ID : 3848
Uniprot ID : P04264
Alternative Name : 67 kDa cytokeratin, Cytokeratin-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRTA
Immunogen Information : Human epidermal keratin

AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

IHC : 1:50-1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Post transnational modification: Undergoes deimination of some arginine residues (citrullination).
Tissue Specificity: The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis.
BioGrid: 110046. 71 interactions.
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