Mouse Monoclonal Antibody to CREB1 (Clone: 1335CT115.203.189)(Discontinued)

Product code: 10-6587

Clone name : 1335CT115.203.189
Clonality : Monoclonal
Application : WB
Reactivity : Human, Mouse, Rat

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Format : Purified
Amount : 400 µl
Isotype : Mouse IgG1,Kappa
Purification : Protein G Chromatography
Content : Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Storage condition : Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene : CREB1
Gene ID : 1385
Uniprot ID : P16220
Alternative Name : Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1, CREB1
Immunogen Information : Recombinant Protein
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

WB~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
Post transnational modification: Sumoylated with SUMO1. Sumoylation on Lys-304, but not on Lys-285, is required for nuclear localization of this protein. Sumoylation is enhanced under hypoxia, promoting nuclear localization and stabilization.
BioGrid: 107775. 146 interactions.
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