Mouse Monoclonal Antibody to CD30(Clone: Ber-H2)(Discontinued)
Figure 1 : Formalin fixed paraffin embedded Hodgkin’s lymphoma with CD30/Ki-1 antibody ( 10-11540).
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Shipping Info:
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| Format : | T.C. Sup. |
| Amount : | 0.5 ml |
| Isotype : | Mouse IgG1, Kappa |
| Content : | This antibody is supplied as tissue culture supernatant containing sodium azide as preservative. |
| Storage condition : | Store at 2-8°C. |
This antibody recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
IHC : 1:50-1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm |
| Post transnational modification: | Phosphorylated on serine and tyrosine residues. |
| BioGrid: | 107381. 30 interactions. |
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