Monoclonal Antibody to p21 (Clone: WA-1)

Product code: 10-7526

Clone name : WA-1
Clonality : Monoclonal
Application : IHC, WB
Reactivity : Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $90.00 

  • $260.00 

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Shipping Info:

Order now and get it on Thursday December 26, 2024

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1 Kappa
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : CDKN1A
Gene ID : 1026
Uniprot ID : P38936
Alternative Name : CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1
Immunogen Information : Recombinant human p21 protein was used as immunogen to generate the antibody.

p21, a member of the cycle dependent kinase (CDK) inhibitor family, was first identified as a tumor suppressor or anti-oncogenic protein and negative regulator of the cell cycle.

Immunohistochemical analysis: 1:50-1:100, Western blot analysis: 2-4 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Nucleus
Post transnational modification: Acetylation leads to protein stability. Acetylated in vitro on Lys-141, Lys-154, Lys-161 and Lys-163. Deacetylation by HDAC1 is prevented by competitive binding of C10orf90/FATS to HDAC1 (By similarity).
Tissue Specificity: Expressed in all adult tissues, with 5-fold lower levels observed in the brain.
BioGrid: 107460. 284 interactions.
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