Monoclonal Antibody to Mouse CTLA4 (Clone: ABM5C62)
Figure:1- Western blot analysis of Mouse CTLA4. Anti-Mouse CTLA4 antibody (Clone: ABM5C62) was tested at 2 µg/ml on (1) m Brain and (2) 3T3 Lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rat IgG2a, kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
Recommended dilutions: WB: 2-4 µg/ml. However, this need to be optimized based on the research applications.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Post transnational modification: | Phosphorylation at Tyr-201 prevents binding to the AP-2 adapter complex, blocks endocytosis, and leads to retention of CTLA4 on the cell surface. |
| Tissue Specificity: | Widely expressed with highest levels in lymphoid tissues. |
| BioGrid: | 198575. 1 interactions. |
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