Monoclonal Antibody to Mouse CTLA4 (Clone: ABM5C62)

Product code: 10-7630

Clone name : ABM5C62
Clonality : Monoclonal
Application : WB
Reactivity : Mouse

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $110.00 

  • $290.00 

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Shipping Info:

Order now and get it on Friday November 22, 2024

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Format : Purified
Amount : 100 µg
Isotype : Rat IgG2a, kappa
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : Ctla4
Gene ID : 12477
Uniprot ID : P09793
Alternative Name : Cytotoxic T-lymphocyte-associated antigen 4, CD152
Immunogen Information : Full length recombinant Mouse CTLA4 protein was used as the immunogen for this antibody.

Recommended dilutions: WB: 2-4 µg/ml. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Post transnational modification: Phosphorylation at Tyr-201 prevents binding to the AP-2 adapter complex, blocks endocytosis, and leads to retention of CTLA4 on the cell surface.
Tissue Specificity: Widely expressed with highest levels in lymphoid tissues.
BioGrid: 198575. 1 interactions.
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