Monoclonal Antibody to IL-17RE (Clone: ABM2G70)
Figure-1: Western blot analysis of IL-17RE. Anti-IL-17RE antibody (Clone: ABM2G70) was tested at 2 µg/ml on (1) Jurkat, (2) PC3 and (3) NIH3T3 lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG2b Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
IL-17RE (Interleukin 17 receptor E) is an orphan receptor of the IL-17 receptor family. The members of this receptor family play a critical role in inflammatory responses and contribute to the pathology of many autoimmune diseases. IL-17RE is a receptor specific to IL-17C preferentially expressed on tissue epithelial cells and regulates early innate immunity to intestinal pathogens by signaling to downstream components of the mitogen activated protein kinase (MAPK) pathway.
Western blot analysis: 2-4 µg/ml, Flowcytometric analysis- 2-4 µg/10^6 Cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Tissue Specificity: | Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines. |
| BioGrid: | 126304. 12 interactions. |
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