Monoclonal Antibody to Human ATF2 (Clone: ABM16E7)

Product code: 10-1032

Clone name : ABM16E7
Clonality : Monoclonal
Application : WB
Reactivity : Mouse, Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $110.00 

  • $290.00 

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Shipping Info:

Order now and get it on Wednesday November 06, 2024

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1, kappa
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : ATF2
Gene ID : 1386
Uniprot ID : P15336
Alternative Name : Cyclic AMP-dependent transcription factor ATF-2 , cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, HB16, Histone acetyltransferase ATF2, cAMP response element-binding protein CRE-BP1
Immunogen Information : A partial length recombinant protein of human ATF2 was used as immunogen for this antibody.

WB: 4-6 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus, Cytoplasm, Mitochondrion outer membrane
Post transnational modification: Phosphorylation of Thr-69 by MAPK14 and MAPK11, and at Thr-71 by MAPK1/ERK2, MAPK3/ERK1, MAPK11, MAPK12 and MAPK14 in response to external stimulus like insulin causes increased transcriptional activity. Phosphorylated by PLK3 following hyperosmotic stress. Also phosphorylated and activated by JNK and CaMK4. ATM-mediated phosphorylation at Ser-490 and Ser-498 stimulates its function in DNA damage response. Phosphorylation at Ser-62, Thr-73 and Ser-121 activates its transcriptional activity. Phosphorylation at Thr-69 or Thr-71 enhances its histone acetyltransferase (HAT) activity.
Tissue Specificity: Ubiquitously expressed, with more abundant expression in the brain.
BioGrid: 107776. 213 interactions.
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