Monoclonal Antibody to Ep-CAM / CD326 (Epithelial Marker)(Clone : EGP40/837)

Product code: 36-1410

Clone name : EGP40/837
Clonality : Monoclonal
Application : FACS, IF, WB, IHC
Reactivity : Human
Conjugate : PE

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0.5 ml
$520.00 

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG1, kappa
Purification : Affinity Chromatography
Content : PE conjugated Ep-CAM / CD326 Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.
Storage condition : Store the antibody at 4°C; stable for 6 months.
Gene : EPCAM
Gene ID : 4072
Uniprot ID : P16422
Alternative Name : EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
Immunogen Information : Recombinant full-length human TACSTD1 protein

EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Lateral cell membrane, Cell junction
Post transnational modification: Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability.
BioGrid: 110250. 5 interactions.
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