Anti-Vinculin Monoclonal Antibody (Clone: hVIN-1)

Product code: 39-1053

Clone name : hVIN-1
Clonality : Monoclonal
Application : WB, IHC-F
Reactivity : Human

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Size
Price
100 μg/vial
$622.00 

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Amount : 100 μg/vial
Isotype : Mouse IgG1
Purification : Ascites
Content : Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage condition : At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Gene : Vcl
Gene ID : 305679
Uniprot ID : P85972
Alternative Name : Vinculin ; Metavinculin ; Vcl
Immunogen Information : Human vinculin, purified from uterus.

Vinculin is a cytoskeletal protein associated with the cytoplasmic face of both cell-cell and cell-extracellular matrix adherens-type junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Both human and chicken embryo sequences of vinculin contain 1,066 amino acids and, furthermore, that the 2 proteins exhibit a high level of sequence identity(greater than 95%). Vinculinis mapped to 10q22.1-q23.

Western blot : 1-2μg/ml; Immunohistochemistry(Frozen Section) : 2-4μg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Cell junction, Cell junction, Cytoplasm, Cell membrane
Post transnational modification: Acetylated; mainly by myristic acid but also by a small amount of palmitic acid.
BioGrid: 258242. 2 interactions.
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