Anti-Gelsolin Monoclonal Antibody (Clone: GS-2C4)

Product code: 39-1038

Clone name : GS-2C4
Clonality : Monoclonal
Application : WB, IHC-P, IHC-F
Reactivity : Human

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100 μg/vial
$622.00 

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Amount : 100 μg/vial
Isotype : Mouse IgG1
Purification : Ascites
Content : Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage condition : At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Gene : Gsn
Gene ID : 296654
Uniprot ID : Q68FP1
Alternative Name : Gelsolin; Actin-depolymerizing factor; ADF; Brevin; Gsn
Immunogen Information : Human plasma gelsolin.

Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.

Western blot : 0.5-1μg/ml; Immunohistochemistry(Paraffin-embedded Section) : 1-2μg/ml; Immunohistochemistry(Frozen Section) : 1-2μg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: Phosphorylated on tyrosine residues in vitro.
BioGrid: 255439. 2 interactions.
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