Anti-Catenin gamma (Plakoglobin) Monoclonal Antibody (Clone: 15F11)
Figure 1: Anti-Catenin gamma(Plakoglobin) monoclonal antibody(39-1011). Western blotting: Lane 1: MCF-7 Cell Lysate, Lane 2: HELA Cell Lysate , Lane 3: MM231 Cell Lysate, Lane 4: HT1080 Cell Lysate.
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| Amount : | 100 μg/vial |
| Isotype : | Mouse IgG1 |
| Purification : | Ascites |
| Content : | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
Junction Plakoglobin(JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.
Western blot : 2μg/ml; Immunohistochemistry(Frozen Section) : 4μg/ml; Immunocytochemistry : 1μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell junction, Cell junction, Cytoplasm, Membrane |
| Post transnational modification: | May be phosphorylated by FER. |
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