Anti-PMS2 Monoclonal Antibody (Clone:IHC412)(Discontinued)

Product code: 44-1071

Clone name : IHC412
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG1
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : PMS2
Gene ID : 5395
Uniprot ID : P54278
Alternative Name : PMS2, PMSL2
Immunogen Information : Recombinant Human PMS2

Postmeiotic Segregation Increased 2 (PMS2) is a DNA repair protein involved in mismatch repair. Mutations and deficiencies in the PMS2 gene have been linked to microsatellite instability, and malignancies such as hereditary nonpolyposis colorectal cancer and endometrial cancer. Anti-PMS2 is recommended to be used as part of a panel along with antibodies against MLH1, MSH2, and MSH6.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
BioGrid: 111404. 55 interactions.
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