Anti-Lysozyme Monoclonal Antibody (Clone:LZ598-10G9)
Figure 1: Intracellular staining (mass cytometry) of PBMC after Ficoll-Paque separation with anti-human lysozyme (LZ598-10G9) Gd155. Gated on native.
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
Lysozyme is anti-bacterial enzyme found mainly in milk, saliva, tears, plasma, spleen, mucus, and leukocytes (e.g. in cytoplasmic granules of neutrophils). It damages bacterial cell walls by hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Lysozyme is part of the innate immune system. It protects wet body surfaces, such as conjunctiva. Reduced lysozyme levels have been associated with bronchopulmonary dysplasia in newborns. On the other hand high lysozyme blood levels produced for example by myelomonocytic leukemia cells can lead to kidney failure and low blood potassium.
| Subcellular location: | Secreted |
| Post transnational modification: | The processed form derives from the membrane form by proteolytic processing. |
| Tissue Specificity: | The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta. |
| BioGrid: | 110247. 42 interactions. |
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