Anti-Human CD303 Mab (Clone:15E3)

Product code: 30-2877

Clone name : 15E3
Clonality : Monoclonal
Application : IHC-Fr, ICC, ELISA, FACS
Reactivity : Human

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0.1 mg
$398.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1 kappa
Purification : Purified by protein-A affinity chromatography.
Content : Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Concentration : 1 mg/ml
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CLEC4C
Gene ID : 170482
Uniprot ID : Q8WTT0
Alternative Name : BDCA2, CLEC4C, DLEC, HECL, CLECSF7, CLECSF11, PRO34150
Immunogen Information : CD303 ectodomain fused with human IgG Fc domain

Specificity : The mouse monoclonal antibody 15E3 recognizes an extracellular epitope of human CD303, a transmembrane glycoprotein expressed on plasmacytoid dendritic cells.

CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.

Flow cytometry: Recommended dilution: 1-5 μg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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