Anti-Human CD303 Mab (Clone:15E3)
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD303 (15E3) purified antibody (concentration in sample 3 μg/ml, GAM FITC).
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Format : | Purified |
Amount : | 0.1 mg |
Isotype : | Mouse IgG1 kappa |
Purification : | Purified by protein-A affinity chromatography. |
Content : | Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide Concentration : 1 mg/ml |
Storage condition : | Store at 2-8°C. Do not freeze. |
Specificity : The mouse monoclonal antibody 15E3 recognizes an extracellular epitope of human CD303, a transmembrane glycoprotein expressed on plasmacytoid dendritic cells.
CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.
Flow cytometry: Recommended dilution: 1-5 μg/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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