Anti-Human CD231 Antibody (Clone : B2D)

Product code: 30-2616

Clone name : B2D
Clonality : Monoclonal
Application : FACS , IP, WB, IHC
Reactivity : Human

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0.1 mg
$389.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified from cell culture supernatant by protein-A affinity chromatography
Content : 1 mg/ml
Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : TSPAN7
Gene ID : 7102
Alternative Name : TSPAN7, TALLA-1, MXS1, MRX58, TM4SF2,tetraspanin 7
Immunogen Information : Human T-ALL cell line THP-6
CD231 (TALLA-1, T-ALL-asociated antigen 1), also known as tetraspanin 7, is a 150 kDa (under reducing conditions 32-45 kDa) transmembrane glycoprotein of tetraspanin family, expressed in T-type acute lymphoblastic leukemia, neuroblastoma, and neuronal tissue. Mutations of CD231 gene are associated with X-linked mental retardation, Huntington´s chorea, and myotonic dystrophy. CD231 interacts with integrins and may have a role in the control of neurite outgrowth. Antibodies to CD231 are important for detection of T-ALL and are potential targets of its treatment.
Specificity : The mouse monoclonal antibody B2D recognizes an extracellular epitope of CD231 (TALLA-1, tetraspanin 7), a transmembrane glycoprotein expressed in neuronal tissue and T-ALL.
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