Anti-Hu TCR Vdelta2 Purified
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human TCR Vdelta2 (B6) purified antibody
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| Format : | Purified |
| Amount : | 0.1 mg |
| Purification : | Purified by protein-A affinity chromatography. |
| Content : | Concentration: 1 mg/ml Storage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Alternative Name : | TCRVD2 |
| Immunogen Information : | human recombinant TCR Vdelta2 |
TCR Vdelta2 is a variant of TCR delta chain, that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells, Vdelta2 T cells express MHC I receptors and killer Ig-like receptors, that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56.
Specificity :The mouse monoclonal antibody B6 recognizes an extracellular epitope of human TCR Vdelta2, which is expressed on the majority of gamma/delta T cells.
Flow cytometry: Recommended dilution: 1-4 µg/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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