Anti-Hu CD118 (Clone: 12D3) Purified

Product code: 30-2833

Clone name : 12D3
Clonality : Monoclonal
Application : ELISA, FACS, WB
Reactivity : Human

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0.1 mg
$398.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1 kappa
Purification : Purified by protein-A affinity chromatography.
Content : Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline (PBS), pH 7.4
Storage condition : Store at 2-8°C. Do not freeze.
Gene : LIFR
Gene ID : 3977
Uniprot ID : P42702
Alternative Name : LIF receptor subunit alpha LIFR alpha, SWS, SJS2, STWSm, gp190
Immunogen Information : human recombinant soluble CD118-Fc

CD118 (LIFR alpha) is a type I transmembrane glycoprotein of the cytokine receptor family, which associates noncovalently with CD130 to form the functional high affinity LIF receptor, which also acts as an oncostatin M receptor. CD118 alone binds LIF with low affinity. A secreted form of CD118 results from alternative splicing, and may have inhibitory effect, as it also binds LIF, although with low affinity. CD118 is not expressed on lymphocytes, but it is widely expressed outside the immune system. Soluble CD118 level rises during pregnancy, in parallel with a drop in circulating LIF levels.
Specificity :The mouse monoclonal antibody 12D3 recognizes an extracellular epitope of CD118, a transmembrane glycoprotein, which associates with CD130 to form the functional high affinity LIF receptor.

Flow cytometry: Recommended dilution: 2-5 µg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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