Anti-EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody(Clone: GFR/2341)

Name: Anti-EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody(Clone: GFR/2341)
Brand: Abeomics
SKU: 36-2196
Price: 520.0000 USD
Availability: InStock
Rating: 4.9 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Lung SqCC stained with EGFR Mouse Monoclonal Antibody (GFR/2341).

Anti-EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody(Clone: GFR/2341)

Roll over image to zoom in

Fig. 1: Formalin-fixed, paraffin-embedded human Lung SqCC stained with EGFR Mouse Monoclonal Antibody (GFR/2341).

Fig. 2: Formalin-fixed, paraffin-embedded human Placenta stained with EGFR Mouse Monoclonal Antibody (GFR/2341).

Fig. 3: SDS-PAGE Analysis Purified EGFR Mouse Monoclonal Antibody (GFR/2341). Confirmation of Integrity and Purity of Antibody.

Fig. 4: Analysis of Protein Array containing more than 19,000 full-length human proteins using EGFR Mouse Monoclonal Antibody (GFR/2341) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2196

Clone name :	GFR/2341
Clonality :	Monoclonal
Application :	WB, IHC
Reactivity :	Human

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Write a review for this product on BioCompare

Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	EGFR
Gene ID :	1956
Uniprot ID :	P00533
Alternative Name :	Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
Immunogen Information :	Recombinant fragment of human EGFR protein (around aa 344-492) (exact sequence is proprietary)

This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews

Write a review on this product!