Anti-Cyclin E (G1/S-Phase Cyclin) Monoclonal Antibody(Clone: CCNE1/2587)
Fig. 1: SDS-PAGE Analysis Purified Cyclin E Mouse Monoclonal Antibody (CCNE1/2587). Confirmation of Integrity and Purity of Antibody.
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| Amount : | 100 µg |
| Isotype : | Mouse IgG, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress throµgh S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.
ELISA (For coating, order Ab without BSA);
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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