PE Conjugated, Anti-CLIC5a Monoclonal Antibody (Clone:CLIC5-02)

Product code: 30-2345

Clone name : CLIC5-02
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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0.1 mg
$468.00 

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Amount : 0.1 mg
Isotype : Mouse IgG2b
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CLIC5
Gene ID : 53405
Uniprot ID : Q9NZA1
Alternative Name : CLIC5
Immunogen Information : KLH-conjugated peptide corresponding to the amino acids 160-173 of human CLIC5a

CLIC5a belongs to the family of chloride intracellular channel (CLIC) proteins, all sharing a highly conserved C terminus and variable N terminus. Human CLIC5 is transcribed in two isoforms, 32 kDa CLIC5a (251 amino acids) and 49 kDa CLIC5b (410 amino acids). These proteins exist in a soluble form and their function as ion channels in vitro has not been fully confirmed in vivo. CLIC5a is a component of complexes of actin, ezrin, and several other actin-associated proteins and is important for functionality of actin-based structures.

Subcellular location: Golgi apparatus, Cytoplasm, Membrane
Tissue Specificity: Widely expressed in both fetal and adult human tissues (PubMed:24781754). Isoform 1 is expressed in renal glomeruli endothelial cells and podocytes (at protein level).
BioGrid: 119781. 7 interactions.
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