Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAb

Product code: 12-9460

Clone name : DMC484
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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Available Pack Size(s)

  •   10 µg

  •   100 µg

  • $355.00 

  • $637.00 

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Amount : 100 µg
Isotype : Rabbit/Human Fc chimeric IgG1
Purification : Purified from cell culture supernatant by affinity chromatography
Content : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage condition : Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Uniprot ID : P12830
Alternative Name : Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO
Description :Anti-CDH1 antibody(DMC484); IgG1 Chimeric mAb
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats; a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric; breast; colorectal; thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation; invasion; and:or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq; Nov 2015]

FACS 1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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