Anti-CD40 Monoclonal Antibody (Clone:HI40a)-FITC Conjugated

Product code: 30-2002

Clone name : HI40a
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : FITC

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Price
100 tests
$433.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD40
Gene ID : 959
Uniprot ID : P25942
Alternative Name : B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40
Immunogen Information : Human CD40a
CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell types, such as B cells, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts or vascular smooth muscle cells. Interaction of CD40 and its ligand CD154 (CD40L) is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. In monocytes/macrophages CD40 engagement induces production of pro-inflammatory cytokines and chemokines. CD40-CD154 interactions are also critical for development of CD4 T cell-dependent effector functions. CD40 links innate and adaptive immune responses to bacterial stimuli and serves as an important regulator affecting functions of other costimulatory molecules.
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