PE Conjugated, Anti-CD28 Monoclonal Antibody (Clone:CD28.2)

Product code: 30-2267

Clone name : CD28.2
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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Price
100 tests
$468.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD28
Gene ID : 940
Uniprot ID : P10747
Alternative Name : CD28
Immunogen Information : DC28.1.3.3 murine T cell hybridoma transfected with human CD28 cDNA

CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Subcellular location: Cell surface
Post transnational modification: CD40LG induces tyrosine phosphorylation of isoform 3.
Tissue Specificity: Expressed in T-cells and plasma cells, but not in less mature B-cells.
BioGrid: 107378. 20 interactions.
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