Anti-CD161 Monoclonal Antibody (Clone:HP-3G10)-APC Conjugated
Figure 1: Surface staining of human peripheral blood cells using anti-CD161 (HP-3G10) APC.
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Shipping Info:
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| Amount : | 100 tests |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on a majority of NK cells, NKT cells, and e.g. Th17 cells and CD3+ thymocytes. Although rat CD161 has three isoforms (a, b, c), the human CD161 is expressed as one isoform.
| Subcellular location: | Membrane |
| Post transnational modification: | N-glycosylated. Contains sialic acid residues. |
| Tissue Specificity: | Expressed in a subset of NK cells predominantly in intestinal epithelium and liver. Detected in peripheral blood T-cells and preferentially in adult T-cells with a memory antigenic phenotype. |
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