Anti-c-Myb Oncoprotein Monoclonal Antibody(Clone: MYB286)

Product code: 36-2830

Clone name : MYB286
Clonality : Monoclonal
Application : ELISA
Reactivity : Human

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Available Pack Size(s)

  •   20 µg

  •  100 µg

  • $270.00 

  • $520.00 

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Amount : 100 µg
Isotype : Mouse IgG1, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : MYB
Gene ID : 4602
Uniprot ID : P01104
Alternative Name : c-myb_CDS; efg; ONCOGENE AMV; Oncogene MYB; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog
Immunogen Information : A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb onco protein, coupled to KLH
The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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