TNF-alpha, Soluble (human) (Recombinant)

Product code: 32-190047

Application : Functional Assay
Reactivity : Human

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Available Pack Size(s)

  •   50 µg

  •  10 µg

  • $325.00 

  • $263.00 

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Amount : 10 µg
Purification : >=95% (SDS-PAGE)
Content : 10 µg size: Reconstitute with 100 µl sterile water.
50 µg size: Reconstitute with 50 µl sterile water.
PBS containing at least 0.1% BSA should be used for further dilutions.10 µg size: 0.1 mg/ml after reconstitution.
50 µg size: 1 mg/ml after reconstitution.
Lyophilized. Contains PBS.
Storage condition : Short Term Storage +4°C ; Long Term Storage-20°C ;After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
PBS containing at least 0. 1% BSA should be used for further dilutions. Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Alternative Name : Tumor Necrosis Factor Ligand Superfamily Member 2; Cachectin

A FLAG®-tag is fused at the N-terminus of human TNF-alpha (aa 85-223).Specific Binds to human and mouse TNF-R1.Tumor necrosis factor (TNF, cachexin or cachectin and formerly known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha, whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha (MultimericTNF-alpha (32-190048). Since the MultimericTNF-alpha mimics the membrane-bound form (forms oligomers higher than trimer), it is the only TNF-alpha protein that can activate the TNF-R2. For TNF-R1 activation, either "normal" TNF-alpha or Multimeric TNF-alpha can be used.

MW :~17kDa (SDS-PAGE)
Biological Activity: Induces cell death at a concentration range of 0.01-10ng/ml (ED50= 0.05ng/ml or 2 x 10E7 Units/mg; WEHI 164 cells).
Endotoxin Content: <0.01EU/µg purified protein (LAL test; Lonza).

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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