ABEOMICS custom TNF-alpha reporter assay utilizes the proprietary TNF-alpha reporter cell line system. TNF-alpha is a cytokine produced primarily by macrophages and promotes the inflammatory responses associated with autoimmune disorders. TNF-alpha reporter system is designed to monitor the TNF-alpha promoter activity. TNF-alpha reporter assay services include screening of agonists/antagonists that affect the TNF-alpha induction, EC50/IC50 evaluation of those agonists/inhibitors/inhibitory antibodies, and functional analysis of TNF-alpha induction-related signaling pathways. Assay results will contain a written report and downloadable Excel- or Prism-based data.
