STAT5 Reporter Assay

ABEOMICS custom STAT5 reporter assay utilizes the proprietary STAT5 reporter cell line system. Signal Transducer and Activator of Transcription 5 (STAT5) is involved in regulation of cell cycle, apoptosis and proliferation. Aberrant STAT5 activity is closely related to a wide range of human cancers as  STAT5 is often found to be constitutively phosphorylated in cancer cells. STAT5 reporter system is designed to monitor the STAT5 transcriptional activity. STAT5 reporter assay services include screening of STAT5 agonists/antagonists, EC50/IC50 evaluation of those molecules, and functional analysis of STAT5 signaling pathways. Assay results will contain a written report and downloadable Excel- or Prism-based data.